Opportunity Information: Apply for RFA FD 25 019
The Food Safety Capacity and Infrastructure Building (U2F) opportunity (RFA FD 25 019) is a discretionary funding program from the U.S. Food and Drug Administration (FDA) designed to strengthen national food safety work by investing in shared tools and infrastructure. The core aim is to fund the development, ongoing support, and broader promotion of innovative information-sharing and research capabilities that live on the Integrated Food Safety System (IFSS) collaboration and research portal. That portal functions as a central federal-state workspace where partners can coordinate, exchange data and insights, and accelerate efforts that protect public health by preventing or responding more effectively to food safety risks.
This award uses a cooperative agreement funding instrument, which generally means the FDA expects to be substantially involved during the project period, not just providing funds and receiving reports. In practice, that often includes close coordination with FDA staff on technical direction, alignment with national IFSS priorities, and ensuring that portal-based tools are usable and adopted by the intended community of federal, state, and other public health and food protection partners. The program sits in the Agriculture, Consumer Protection, Food and Nutrition activity area, and is associated with CFDA number 93.103.
Eligibility is highly limited. Only current recipients funded under RFA-FD-20-023 are allowed to apply, so this is essentially a continuation or expansion opportunity targeted to an existing awardee community rather than an open competition to new organizations. The listing identifies eligible applicants as "Others," but the controlling eligibility restriction is the requirement of current award status under the earlier RFA.
Funding is expected to support one award, with an award ceiling of $1,000,000. The original application closing date is August 1, 2025, and the opportunity record was created on July 11, 2025. Overall, the grant is focused less on direct field inspections or enforcement and more on the shared digital and collaborative backbone of the IFSS ecosystem, with the goal of making food safety partners more connected, better informed, and faster at translating information into prevention and public health protection.Apply for RFA FD 25 019
- The Food and Drug Administration in the agriculture, consumer protection, food and nutrition sector is offering a public funding opportunity titled "Food Safety Capacity and Infrastructure Building (U2F)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
- This funding opportunity was created on 2025-07-11.
- Applicants must submit their applications by 2025-08-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others.
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Food Safety Capacity and Infrastructure Building (U2F) (RFA FD 25 019) - FAQs
What is the Food Safety Capacity and Infrastructure Building (U2F) opportunity?
The Food Safety Capacity and Infrastructure Building (U2F) opportunity (RFA FD 25 019) is a discretionary funding program from the U.S. Food and Drug Administration (FDA). It is designed to strengthen national food safety work by investing in shared tools and infrastructure that support collaboration and information-sharing.
What is the main purpose of this funding program?
The core purpose is to fund the development, ongoing support, and broader promotion of innovative information-sharing and research capabilities that operate on the Integrated Food Safety System (IFSS) collaboration and research portal. The goal is to improve how food safety partners coordinate, exchange data and insights, and respond to food safety risks to protect public health.
Which federal agency is offering this grant?
This opportunity is offered by the U.S. Food and Drug Administration (FDA).
What type of funding instrument is used for this award?
This award uses a cooperative agreement. That typically means FDA expects to be substantially involved throughout the project period, not only by providing funds but also by coordinating on technical direction, alignment with national IFSS priorities, and adoption and usability of portal-based tools for intended partners.
What does "substantial involvement" from FDA likely mean in practice?
Based on the description provided, substantial involvement may include close coordination with FDA staff on technical direction, ensuring project activities align with national IFSS priorities, and working to ensure that tools hosted on the IFSS portal are usable and adopted by the intended community of federal, state, and other public health and food protection partners.
What is the Integrated Food Safety System (IFSS) collaboration and research portal?
The IFSS collaboration and research portal is described as a central federal-state workspace. It is intended to help partners coordinate, exchange data and insights, and accelerate efforts that prevent or more effectively respond to food safety risks.
What kinds of projects or activities are emphasized by this opportunity?
The opportunity emphasizes building shared digital and collaborative infrastructure. It focuses on developing and supporting tools, information-sharing capabilities, and research functions that live on the IFSS collaboration and research portal, along with promoting broader use of those capabilities among food safety partners.
Is this funding intended for direct inspections, enforcement, or field operations?
The description indicates the grant is focused less on direct field inspections or enforcement and more on strengthening the shared digital and collaborative backbone of the IFSS ecosystem. Its intent is to make partners more connected, better informed, and faster at translating information into prevention and public health protection.
What is the activity area associated with this opportunity?
The opportunity is listed under the Agriculture, Consumer Protection, Food and Nutrition activity area.
What is the CFDA number associated with this program?
The program is associated with CFDA number 93.103.
Who is eligible to apply?
Eligibility is highly limited. Only current recipients funded under RFA-FD-20-023 are allowed to apply. This makes it a continuation or expansion opportunity for an existing awardee community rather than an open competition for new organizations.
The listing says eligible applicants are "Others." What does that mean here?
While the listing identifies eligible applicants as "Others," the controlling eligibility requirement described is that the applicant must be a current recipient funded under RFA-FD-20-023.
How many awards does FDA expect to make?
Funding is expected to support one award.
What is the maximum funding amount (award ceiling)?
The award ceiling is $1,000,000.
When is the application due?
The original application closing date is August 1, 2025.
When was the opportunity record created?
The opportunity record was created on July 11, 2025.
What is the overall public health impact this opportunity is trying to achieve?
The opportunity aims to protect public health by strengthening the ability of federal, state, and other food protection partners to share information, coordinate work, and move more quickly from insights to prevention or response when food safety risks arise.
Who are the intended users or beneficiaries of the portal-based tools supported by this grant?
The intended community includes federal, state, and other public health and food protection partners who use the IFSS collaboration and research portal to coordinate and share information.
What does it mean that this is a discretionary funding program?
The opportunity is described as a discretionary funding program, meaning it is a competitively awarded (as applicable within its eligibility limits) grant/cooperative agreement program where FDA chooses to invest in specific priorities. In this case, the priority is strengthening shared tools and infrastructure supporting the IFSS portal ecosystem.
Is this opportunity open to organizations that have never received RFA-FD-20-023 funding?
No. Based on the information provided, only current recipients funded under RFA-FD-20-023 are eligible to apply.
What does "ongoing support" imply for the tools and capabilities built under this award?
As described, the program is not only about developing new capabilities but also supporting them over time and promoting broader adoption. This suggests the funded work is expected to keep tools functioning, relevant, and usable on the IFSS portal rather than being a one-time build.
What does "broader promotion" refer to in the context of this grant?
The opportunity highlights broader promotion of the information-sharing and research capabilities hosted on the IFSS portal. Based on the description, this refers to increasing awareness, usability, and adoption of portal-based tools among the intended community of partners.
What is the central hub or platform this grant is expected to support?
The central platform is the Integrated Food Safety System (IFSS) collaboration and research portal, which serves as a shared workspace for cross-jurisdiction food safety collaboration.
What is the opportunity identifier?
The opportunity is identified as RFA FD 25 019.
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| Applied Regulatory Science Research to Evaluate Cardiotoxicity of Oncology Therapeutics (U01) Clinical Trial Optional Apply for RFA FD 25 015 Funding Number: RFA FD 25 015 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $500,000 |
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