Opportunity Information: Apply for RFA FD 25 019
The Food Safety Capacity and Infrastructure Building (U2F) opportunity (RFA FD 25 019) is a discretionary funding program from the U.S. Food and Drug Administration (FDA) designed to strengthen national food safety work by investing in shared tools and infrastructure. The core aim is to fund the development, ongoing support, and broader promotion of innovative information-sharing and research capabilities that live on the Integrated Food Safety System (IFSS) collaboration and research portal. That portal functions as a central federal-state workspace where partners can coordinate, exchange data and insights, and accelerate efforts that protect public health by preventing or responding more effectively to food safety risks.
This award uses a cooperative agreement funding instrument, which generally means the FDA expects to be substantially involved during the project period, not just providing funds and receiving reports. In practice, that often includes close coordination with FDA staff on technical direction, alignment with national IFSS priorities, and ensuring that portal-based tools are usable and adopted by the intended community of federal, state, and other public health and food protection partners. The program sits in the Agriculture, Consumer Protection, Food and Nutrition activity area, and is associated with CFDA number 93.103.
Eligibility is highly limited. Only current recipients funded under RFA-FD-20-023 are allowed to apply, so this is essentially a continuation or expansion opportunity targeted to an existing awardee community rather than an open competition to new organizations. The listing identifies eligible applicants as "Others," but the controlling eligibility restriction is the requirement of current award status under the earlier RFA.
Funding is expected to support one award, with an award ceiling of $1,000,000. The original application closing date is August 1, 2025, and the opportunity record was created on July 11, 2025. Overall, the grant is focused less on direct field inspections or enforcement and more on the shared digital and collaborative backbone of the IFSS ecosystem, with the goal of making food safety partners more connected, better informed, and faster at translating information into prevention and public health protection.Apply for RFA FD 25 019
- The Food and Drug Administration in the agriculture, consumer protection, food and nutrition sector is offering a public funding opportunity titled "Food Safety Capacity and Infrastructure Building (U2F)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
- This funding opportunity was created on 2025-07-11.
- Applicants must submit their applications by 2025-08-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others.
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Applicants who have applied for this opportunity (RFA FD 25 019) also looked into and applied for these:
| Funding Opportunity |
|---|
| Conformance with the Egg Regulatory Program Standards Apply for RFA FD 25 021 Funding Number: RFA FD 25 021 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $47,000 |
| Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional) Apply for RFA FD 25 017 Funding Number: RFA FD 25 017 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $600,000 |
| NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens Apply for PAR 25 014 Funding Number: PAR 25 014 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $200,000 |
| Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required) Apply for RFA FD 25 020 Funding Number: RFA FD 25 020 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $900,000 |
| Reducing Fraud and Lowering Barriers to the Production of Drugs in Shortage by Outsourcing Facilities Apply for RFA FD 25 023 Funding Number: RFA FD 25 023 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $3,000,000 |
| FDA's Integrated Food Safety System Training Delivery and Development Apply for RFA FD 25 016 Funding Number: RFA FD 25 016 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $1,000,000 |
| Establishing the Integrated Food Safety System (IFSS) Regulatory and Laboratory Training System (RLTS) National Coordination Center (NCC) and Learning Management System (LMS) Apply for RFA FD 25 005 Funding Number: RFA FD 25 005 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $1,750,000 |
| Applied Regulatory Science Research to Evaluate Cardiotoxicity of Oncology Therapeutics (U01) Clinical Trial Optional Apply for RFA FD 25 015 Funding Number: RFA FD 25 015 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $500,000 |
| Federal and State Integration Activities to Advance Cooperation and Regulatory Standards Among Animal Food Safety Regulatory Programs Apply for RFA FD 25 022 Funding Number: RFA FD 25 022 Agency: Food and Drug Administration Category: Agriculture, Consumer Protection, Food and Nutrition Funding Amount: $600,000 |
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