Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed) | PAR 22 153

Opportunity Information: Apply for PAR 22 153

The National Institutes of Health (NIH), through the Fogarty International Center (FIC), is offering a discretionary grant opportunity called "Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)" (Funding Opportunity Number PAR-22-153). The core purpose is to build and strengthen the long-term scientific and operational capacity of institutions in low- and middle-income countries (LMICs) so they can conduct high-quality HIV research that matches the realities of their local and national HIV epidemics. Rather than funding clinical trials, this program focuses on the behind-the-scenes research infrastructure that makes strong, ethical, well-managed HIV research possible and sustainable.

A defining feature of this opportunity is its emphasis on collaborative partnerships between U.S. institutions and LMIC institutions. The intent is for applicants to design and deliver targeted training that upgrades practical skills, administrative systems, and financial management capabilities within LMIC research environments. The program is structured around six specific infrastructure functions that NIH considers critical to a reliable research ecosystem. These are: (1) research administration and management, (2) research integrity oversight, (3) ethical review of research to protect human subjects, (4) laboratory animal welfare oversight, (5) health sciences library and information services, and (6) information and communications technology (ICT) systems that support research. Proposed programs are expected to concentrate on building expertise in one of these areas, ensuring the training is deep, usable, and tied to real institutional needs.

The grant is positioned as a way to maximize prior investments in global HIV research capacity by strengthening the institutional foundations that help research programs function effectively over time. In practice, that means improving the systems that govern grants management, compliance, ethics review processes, integrity standards, access to scientific literature and data resources, and the digital infrastructure needed for secure and efficient research operations. A key expectation is that training programs will not only benefit the primary LMIC institution but will also expand access to research infrastructure training for others, both within the same country and across other LMICs. This creates a broader multiplier effect, where trained staff and improved systems can support additional institutions and future collaborations.

Eligibility is broad and includes public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both 501(c)(3) and non-501(c)(3)). The opportunity also explicitly highlights eligibility for a range of institution types and partners, including non-U.S. entities (foreign organizations) and several categories of U.S. minority-serving or special-status institutions, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), and Tribally Controlled Colleges and Universities (TCCUs). This inclusive eligibility structure supports the program's broader aim of building equitable, effective partnerships and expanding access to capacity-building resources.

From an administrative standpoint, the funding instrument is a grant, and the activity category is listed under education and health. The opportunity is associated with CFDA numbers 93.121, 93.279, and 93.989. The original closing date provided is 2024-08-22, and the opportunity was created on 2022-04-21. While the provided source data does not list an award ceiling or the expected number of awards, applicants would typically look to the full FOA text and NIH accompanying guidance for budget limits, project period expectations, and review criteria.

Overall, this grant is best understood as an investment in the institutional "scaffolding" that supports credible HIV research: the people, policies, systems, oversight structures, and technical platforms that allow LMIC institutions to plan, run, manage, and govern HIV research programs to international standards. The explicit "Clinical Trials Not Allowed" designation makes it clear the program is designed to strengthen research infrastructure and training capacity rather than to directly conduct intervention trials.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.279, 93.989.
• This funding opportunity was created on 2022-04-21.
• Applicants must submit their applications by 2024-08-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.

Apply for PAR 22 153

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