Opportunity Information: Apply for RFA HL 19 007

This NIH funding opportunity (RFA HL 19 007) is a limited competition cooperative agreement (U01; clinical trials not allowed) to support a Data Analysis and Coordination Center (DACC) for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS). The MACS and WIHS are long-running U.S. cohort studies focused on HIV, and this announcement is aimed at funding the centralized hub that manages and coordinates the combined cohort study data infrastructure, analytic support, and consortium-wide coordination. In practical terms, the DACC is expected to serve as the backbone for high-quality, standardized data operations across the consortium so researchers can more effectively study HIV infection in the United States, especially the basic and clinical science questions and the epidemiology of HIV-related comorbidities.

The DACC role is positioned as an active member of the MACS/WIHS-CCS consortium rather than a passive data warehouse. The center would typically be responsible for coordinating data collection standards and harmonization across participating clinical sites, ensuring consistent data definitions, maintaining data quality control processes, supporting secure data management and documentation, and enabling reliable analytic workflows for consortium science. Because the scientific focus explicitly includes HIV-related comorbidities, the center would also be expected to support analyses that span aging, cardiovascular and pulmonary complications, cancer and other chronic conditions, co-infections, and other health outcomes that increasingly shape the lives of people with HIV. The DACC would also support the consortium by producing datasets, analytic files, reports, and cross-site summaries that help investigators conduct reproducible research and translate cohort observations into publishable scientific findings and, ultimately, improved understanding of HIV disease and its complications in the modern treatment era.

This FOA is paired with a companion cooperative agreement that supports the MACS/WIHS-CCS Clinical Research Sites (CRS). That pairing signals a division of labor: clinical sites focus on participant-facing research activities and data/specimen collection, while the DACC provides the centralized coordination, data stewardship, and analytic capacity that ties the network together. As a U01 cooperative agreement, the award mechanism also implies substantial NIH involvement during the project, with NIH staff typically collaborating with awardees on governance, milestones, consortium priorities, and coordination expectations, consistent with the cooperative agreement model.

Eligibility is restricted, reflecting the limited competition nature of the opportunity. The listing indicates eligible applicants include public and state-controlled institutions of higher education, and the announcement explicitly excludes non-U.S. entities. Foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. Applicants are directed to consult the full funding announcement for precise eligibility and submission requirements.

Key administrative details from the source information include: the sponsoring agency is the National Institutes of Health; the opportunity category is discretionary; the activity category is education and health; and multiple CFDA numbers are associated with the announcement (93.233, 93.242, 93.279, 93.307, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.855, 93.856), reflecting the cross-institute nature of HIV and comorbidity research and the likelihood of involvement by multiple NIH institutes and centers. The announcement was created on 2017-12-22, with an original closing date of 2018-05-02. The award ceiling and expected number of awards are not specified in the provided data, so those details would need to be confirmed in the full FOA text or related NIH documentation.

  • The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Limited Competition: Data Analysis and Coordination Center for the MACS/WIHS Combined Cohort Study, MACS/WIHS-CCS (U01 Clinical Trials Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.242, 93.279, 93.307, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.855, 93.856.
  • This funding opportunity was created on 2017-12-22.
  • Applicants must submit their applications by 2018-05-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education.
Apply for RFA HL 19 007

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