Opportunity Information: Apply for PAR 22 087

The Food and Drug Administration (FDA), within the Department of Health and Human Services (HHS), offered a fiscal year 2022 discretionary funding opportunity titled "Research to support the development of alternatives to antimicrobials for use in food-producing animals" (Funding Opportunity Number PAR 22 087; CFDA 93.103). The award mechanism is a cooperative agreement, which typically means FDA expects to be more actively involved than it would under a standard grant, often through substantial programmatic collaboration, shared planning, and ongoing technical input during the project period.

The purpose of the opportunity is to fund applied research that helps reduce reliance on antimicrobials in animal agriculture by first clarifying why and where those drugs are most commonly used, and then identifying practical, science-based alternatives. FDA is specifically looking for studies that (1) pinpoint the animal diseases and production circumstances that most strongly drive antimicrobial use in key food-animal sectors, and (2) evaluate or document alternative practices that can meet animal health needs while lowering the need for antimicrobial treatments. The targeted production settings named in the announcement include cattle, swine, turkeys, and chickens, reflecting major U.S. food animal industries where antimicrobial stewardship is a priority.

A central theme of the program is antimicrobial stewardship in veterinary and livestock settings. Rather than focusing only on the drugs themselves, the projects are expected to shed light on management and prevention strategies that can reduce disease pressure and therefore reduce the perceived need for antimicrobial intervention. Examples of relevant alternatives include improved husbandry practices (such as nutrition, housing, stocking density, ventilation, and stress reduction), strengthened biosecurity (to prevent introduction and spread of pathogens), vaccination strategies (to prevent common infectious diseases that prompt treatment), and other preventive or management approaches that support animal health and welfare without routine dependence on antimicrobials. The underlying intent is to generate evidence that can be translated into real-world practice across different farm types and production systems.

This opportunity also ties explicitly to broader federal goals, particularly the National Action Plan objectives related to combating antimicrobial resistance. By engaging the animal health community and other stakeholders, the funded work is meant to advance strategies that foster responsible antimicrobial use and improve the overall understanding of how antimicrobials are used in animal agriculture. In practical terms, FDA is aiming to support studies that can inform guidance, stewardship initiatives, and industry decision-making by identifying the most important disease drivers and the most feasible preventive measures in each production context.

In terms of funding structure, the posted award ceiling is $500,000, with an anticipated total of five awards. The opportunity was created on January 3, 2022, and the original application closing date was March 31, 2022. Eligible applicants are broad and include state, county, and local governments; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and other entities as allowed under the additional eligibility language. This wide eligibility suggests FDA intended to encourage participation from universities, research groups, producer-facing organizations, industry partners, and public sector entities that can access livestock operations and generate actionable findings.

Overall, the grant is designed to produce practical, sector-specific evidence about what is driving antimicrobial use in food animals and what realistic alternatives can reduce that use without compromising animal health. The expected value of the funded research is not only in generating academic knowledge, but in producing findings that can be implemented on farms and integrated into stewardship programs, disease prevention planning, and policy discussions aimed at slowing the development and spread of antimicrobial resistance.

  • The Department of Health and Human Services, Food and Drug Administration in the agriculture, consumer protection, food and nutrition sector is offering a public funding opportunity titled "Research to support the development of alternatives to antimicrobials for use in food-producing animals" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
  • This funding opportunity was created on Jan 03, 2022.
  • Applicants must submit their applications by Mar 31, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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