Opportunity Information: Apply for CDC RFA CK 23 0003
The Centers for Disease Control and Prevention (CDC), within the Department of Health and Human Services (HHS) and specifically NCEZID, announced a discretionary cooperative agreement opportunity called "Strengthening Global Capacity for Molecular Surveillance and Outbreak Response for Enteric Diseases" (Funding Opportunity Number CDC RFA CK 23 0003; CFDA 93.318). The overall aim is to improve how countries and regions detect, track, and respond to enteric diseases by expanding modern laboratory and epidemiologic capabilities, with a strong emphasis on molecular methods and practical outbreak response support. The program is designed to operate across multiple geographic settings, with the specific regional and country locations selected based on CDC priorities.
On the surveillance side, the opportunity focuses on building end-to-end capacity to identify enteric pathogens and understand their spread. A central component is strengthening routine enteric disease surveillance systems, including the ability to confirm cases in the laboratory rather than relying only on syndromic reporting. Another major element is building wastewater and broader environmental surveillance capacity, reflecting the growing use of environmental sampling to detect community transmission and emerging threats earlier than traditional clinical reporting alone. The NOFO also emphasizes regional capability development for whole genome sequencing (WGS), bioinformatics, laboratory diagnosis, and outbreak preparedness. This regional approach is intended to create shared hubs of expertise and infrastructure that can support multiple countries, standardize methods, and speed up cross-border detection of related strains. In addition, the announcement calls for country-level capacity building in WGS and laboratory diagnosis, recognizing that sustainable surveillance requires in-country operational ability to generate, analyze, and use sequencing and diagnostic data for public health decisions.
On the outbreak response side, the opportunity aims to make responses faster, more coordinated, and more effective when enteric outbreaks occur. It includes providing regional technical assistance for enteric disease outbreak response, which can involve guidance on investigation strategies, laboratory surge support, data interpretation, and coordination across jurisdictions when outbreaks affect more than one country. The NOFO also highlights country-level capacity building for Water, Sanitation, and Hygiene (WASH) programs, reflecting the reality that many enteric outbreaks are driven by contaminated water, inadequate sanitation infrastructure, and hygiene gaps, and that long-term prevention requires strengthening those systems. A third outbreak response focus area is workforce development in epidemiology and laboratory practice for enteric diseases, supporting the people and skills needed to run surveillance systems, conduct field investigations, perform diagnostics and sequencing, and translate findings into actionable control measures.
Administratively, this is a cooperative agreement, which generally means CDC expects substantial involvement during the period of performance through collaboration, technical input, and ongoing coordination rather than a hands-off grant structure. Eligible applicants are broad and include state governments, public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses), and other unrestricted entities as listed, subject to any additional eligibility clarifications in the full announcement. The opportunity was created March 15, 2023, with an original application due date of May 14, 2023, and electronically submitted applications required by 11:59 pm Eastern Time on the due date. The CDC anticipated making three awards. The listed award ceiling is shown as 0 in the source data, which typically indicates the ceiling was not provided in that field or was to be specified elsewhere in the full funding notice rather than implying no funding.Apply for CDC RFA CK 23 0003
- The Department of Health and Human Services, Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "Strengthening Global Capacity for Molecular Surveillance and Outbreak Response for Enteric Diseases" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
- This funding opportunity was created on Mar 15, 2023.
- Applicants must submit their applications by May 14, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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| Comprehensive Opioid Recovery Centers Apply for TI 23 020 Funding Number: TI 23 020 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $850,000 |
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| Rural Communities Opioid Response Program – Child and Adolescent Behavioral Health Apply for HRSA 23 041 Funding Number: HRSA 23 041 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $1,000,000 |
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| Rural Health Care Coordination Program Apply for HRSA 23 125 Funding Number: HRSA 23 125 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $300,000 |
| Certified Community Behavioral Health Clinic Planning, Development, and Implementation Grant Apply for SM 23 024 Funding Number: SM 23 024 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,000,000 |
| Certified Community Behavioral Health Clinic Improvement and Advancement Grant Apply for SM 23 016 Funding Number: SM 23 016 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,000,000 |
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| Cooperative Agreement for the Hispanic/Latino Behavioral Health Center of Excellence Apply for FG 23 002 Funding Number: FG 23 002 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,125,000 |
| Health Careers Opportunity Program: The National HCOP Academies Apply for HRSA 23 003 Funding Number: HRSA 23 003 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
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| WISEWOMAN: Well-Integrated Screening and Evaluation of WOMen Across the Nation Apply for CDC RFA DP 23 0003 Funding Number: CDC RFA DP 23 0003 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $2,000,000 |
| American Indian and Alaska Native Behavioral Health Center of Excellence Apply for FG 23 001 Funding Number: FG 23 001 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,500,000 |
| Treatment, Recovery, and Workforce Support Grant Apply for TI 23 021 Funding Number: TI 23 021 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $500,000 |
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